Neuromodulation therapy is vigorously proven to support treatments of various neurological, chronic and mental diseases and disorders.
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Depression is a common mental disorder characterized by persistent sadness and a loss of interest in activities that are typically enjoyable. This tends to lead to an inability to carry out daily activities, erratic sleep habits, loss of appetite (or increased appetite with atypical depression), constant fatigue, etc.
Depression is a common mental disorder. Globally, an estimated 5% of adults suffer from depression. More women are affected by depression than men.
Non-invasive neuromodulation using tDCS.
A migraine is a headache that often affects one side of the head and can be extremely painful, throbbing, or pulsating. It frequently comes with high sensitivity to light and sound as well as nausea and vomiting. The pain can sometimes be so intense that it interferes with your regular activities and can persist for hours or even days.
Migraine is affecting more than 734 million people, or about 10% of the world’s population and is the third-highest cause of disability worldwide in both males and females under the age of 50 years.
Non-invasive neuromodulation using tDCS.
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain and spinal cord process painful and nonpainful signals.
Fibromyalgia has a worldwide presence affecting nearly 1 in 20 people globally. In the United States nearly 2–10% of the general population of all ages are affected by this condition.
Non-invasive neuromodulation using tDCS.
Failed back spine syndrome is the lumbar spinal pain of unknown origin that is either still present after surgery or develops after surgery was performed for spinal pain that originated in the same topographical place.
Estimates of the percentage of adults who experience chronic lower back pain during their lifetime range from 51% to 84%. FBSS is reported to affect between 10 to 40% of patients following back surgery. Increased complexity of back surgery increases the rate of FBSS; failure rates range from 30% to 46% for lumbar fusion and 19% to 25% for microdiscectomy.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Chronic post-surgery pain is an unwanted adverse event in any operation and either manifests itself or becomes more intense, even after the healing process which is usually 3 months. Chronic post-operative pain is one of the most common complications of surgery.
Prevalence of chronic pain among adults ranges from 20.5% to 21.8% and the prevalence of high-impact chronic pain ranges from 6.9% to 7.8%.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Anxiety disorders are characterized by excessive fear and worry and related behavioral disturbances. There are several different kinds of anxiety disorders, such as: generalized anxiety disorder (characterized by excessive worry), panic disorder (characterized by panic attacks), social anxiety disorder (characterized by excessive fear and worry in social situations), separation anxiety disorder (characterized by excessive fear or anxiety about separation from those individuals to whom the person has a deep emotional bond), and others.
An estimated 4.05% of the global population has an anxiety disorder, translating to 301 million people. The number of persons affected has increased by more than 55% from 1990 to 2021.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Bipolar disorder is a mental health condition with extreme mood swings, from emotional highs (you feel euphoric, energized, or excessively irritable) to extreme opposite lows (you could feel melancholy or hopeless and stop enjoying or being interested in most activities). Episodes of mood swings may occur rarely or multiple times a year. While most people will experience some emotional symptoms between episodes, some may not experience any.
In 2019, 40 million people experienced bipolar disorder
Non-invasive neuromodulation using tDCS.
Insomnia is a sleep disorder that can make it difficult to get asleep, keep asleep, or lead you to wake up too early and have trouble falling back asleep. This disorder could negatively affect your health, productivity at work, and quality of life in addition to your energy level and mood.
Chronic insomnia is highly prevalent and affects approximately 30% of the general population.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
A horrific event can cause post-traumatic stress disorder (PTSD), a mental health disease that can be brought on by experiencing it or seeing it. Flashbacks, nightmares, excruciating anxiety, and uncontrollable thoughts about the incident are just a few possible symptoms.
Moderate quality evidence finds the lifetime worldwide prevalence of PTSD in the general population is around 3.9%. In people known to have been exposed to trauma, the rate is 5.6%.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Parkinson’s disease is a chronic condition that affects both the neurological system and the body parts that are under the control of the nervous system. Symptoms emerge gradually, while the initial sign could be a slight tremor in just one hand. Tremors are common, but the disorder may also cause stiffness or slowing of movement.
More than 10 million people worldwide are living with PD. The increases with age, but an estimated four percent of people with PD are diagnosed before age 50.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent damage or deterioration of the nerve fibers.
The estimated number of people with MS worldwide has increased to 2.8 million in 2020.
Non-invasive neuromodulation using tDCS.
Learning Disabilities affect the ability to comprehend, or use spoken or written language, perform mathematical computations, coordinate motions, or focus attention. Even though they can affect very young children, learning problems are typically not identified until the kid is of school age.
The estimate for current learning disabilities among children of ages 3–17 years is 7.8 %, with 3.7 % rated as mild and 4.0 % rated as moderate or severe. Approximately 1,7 % of adults experience learning disabilities.
Non-invasive neuromodulation using tDCS.
Irritable bowel syndrome (IBS) is a common disorder that affects the stomach and intestines, also called the gastrointestinal tract. Symptoms include cramping, abdominal pain, bloating, gas, and diarrhea or constipation, or both. IBS is a chronic condition that you’ll need to manage long term.
Irritable bowel syndrome affects approximately 10-15% of the European population.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
Mild cognitive impairment (MCI) is the stage between the expected decline in memory and thinking that happens with age and the more serious decline of dementia. MCI may include problems with memory, language or judgment.
The overall prevalence of MCI is 15.56% worldwide in adults aged 50 years and older. Prevalence rates of amnestic MCI and non-amnestic MCI is 10.03% and 8.72%.
Non-invasive neuromodulation using tDCS.
Addiction is a compulsive, ongoing, physiological or psychological urge for a habit-forming substance, action, or activity that has negative physical, psychological, or social impacts and usually results in well-defined withdrawal or abstinence symptoms such as anxiety, irritability, tremors, or nausea.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
In most cases cancer pain is caused by the physical damage of some certain structures (tumor pressing on bones, nerves or other organs in the body). Sometimes pain may be due to cancer treatment (some chemotherapy drugs, x-ray therapy).
There are different variants of cancer pain: nerve pain, bone pain, soft tissue pain, phantom pain, referred pain.
Variants of treatment: medications, procedures to block pain signal, integrative therapies.
Non-invasive neuromodulation using a combination of taVNS and tDCS.
ADHD include inattention (not being able to keep focus), hyperactivity (excess movement that is not fitting to the setting) and impulsivity (hasty acts that occur in the moment without thought).
ADHD include inattention (not being able to keep focus), hyperactivity (excess movement that is not fitting to the setting) and impulsivity (hasty acts that occur in the moment without thought).
Non-invasive neuromodulation using tDCS.
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