DISEASE & DISORDER
Depression is a common mental disorder characterized by persistent sadness and a loss of interest in
activities that are typically enjoyable. This tends to lead to an inability to carry out daily activities,
erratic sleep habits, loss of appetite (or increased appetite with atypical depression), constant
fatigue, etc.
Depression is a common mental disorder. Globally, an estimated 5% of adults suffer from
depression. More women are affected by depression than men.
Non-invasive neuromodulation using tDCS “Flow” device.
DISEASE & DISORDER
A migraine is a headache that often affects one side of the head and can be extremely painful,
throbbing, or pulsating. It frequently comes with high sensitivity to light and sound as well as nausea
and vomiting. The pain can sometimes be so intense that it interferes with your regular activities and
can persist for hours or even days.
Migraine is affecting more than 734 million people, or about 10% of the world’s population and is
the third-highest cause of disability worldwide in both males and females under the age of 50 years.
Non-invasive neuromodulation using tDCS “Plato science” device
DISEASE & DISORDER
Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by
fatigue, sleep, memory and mood issues. Researchers believe that fibromyalgia amplifies painful
sensations by affecting the way your brain and spinal cord process painful and nonpainful signals.
Fibromyalgia has a worldwide presence affecting nearly 1 in 20 people globally. In the United States
nearly 2–10% of the general population of all ages are affected by this condition.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Failed back surgery syndrome is the lumbar spinal pain of unknown origin that is either still present
after surgery or develops after surgery was performed for spinal pain that originated in the same
topographical place.
Estimates of the percentage of adults who experience chronic lower back pain during their lifetime
range from 51% to 84%. FBSS is reported to affect between 10 to 40% of patients following back
surgery. Increased complexity of back surgery increases the rate of FBSS; failure rates range from
30% to 46% for lumbar fusion and 19% to 25% for microdiscectomy.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Chronic post-surgery pain is an unwanted adverse event in any operation and either manifests itself
or becomes more intense, even after the healing process which is usually 3 months. Chronic post-
operative pain is one of the most common complications of surgery.
Prevalence of chronic pain among adults ranges from 20.5% to 21.8% and the prevalence of high-
impact chronic pain ranges from 6.9% to 7.8%.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Anxiety disorders are characterized by excessive fear and worry and related behavioral disturbances.
There are several different kinds of anxiety disorders, such as: generalized anxiety disorder
(characterized by excessive worry), panic disorder (characterized by panic attacks), social anxiety
disorder (characterized by excessive fear and worry in social situations), separation anxiety disorder
(characterized by excessive fear or anxiety about separation from those individuals to whom the
person has a deep emotional bond), and others.
An estimated 4.05% of the global population has an anxiety disorder, translating to 301 million
people. The number of persons affected has increased by more than 55% from 1990 to 2021.
DISEASE & DISORDER
Bipolar disorder is a mental health condition with extreme mood swings, from emotional highs (you
feel euphoric, energized, or excessively irritable) to extreme opposite lows (you could feel
melancholy or hopeless and stop enjoying or being interested in most activities). Episodes of mood
swings may occur rarely or multiple times a year. While most people will experience some emotional
symptoms between episodes, some may not experience any.
In 2019, 40 million people experienced bipolar disorder
Non-invasive neuromodulation using tDCS “Flow” device.
DISEASE & DISORDER
Insomnia is a sleep disorder that can make it difficult to get asleep, keep asleep, or lead you to wake
up too early and have trouble falling back asleep. This disorder could negatively affect your health,
productivity at work, and quality of life in addition to your energy level and mood.
Chronic insomnia is highly prevalent and affects approximately 30% of the general population.
Non-invasive neuromodulation using tDCS “Plato science” device.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
DISEASE & DISORDER
A horrific event can cause post-traumatic stress disorder (PTSD), a mental health disease that can be
brought on by experiencing it or seeing it. Flashbacks, nightmares, excruciating anxiety, and
uncontrollable thoughts about the incident are just a few possible symptoms.
Moderate quality evidence finds the lifetime worldwide prevalence of PTSD in the general
population is around 3.9%. In people known to have been exposed to trauma, the rate is 5.6%.
Non-invasive neuromodulation using tDCS “Plato science” device.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
DISEASE & DISORDER
Parkinson's disease is a chronic condition that affects both the neurological system and the body
parts that are under the control of the nervous system. Symptoms emerge gradually, while the initial
sign could be a slight tremor in just one hand. Tremors are common, but the disorder may also cause
stiffness or slowing of movement.
More than 10 million people worldwide are living with PD. The increases with age, but an estimated
four percent of people with PD are diagnosed before age 50.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous
system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers
and causes communication problems between your brain and the rest of your body. Eventually, the
disease can cause permanent damage or deterioration of the nerve fibers.
The estimated number of people with MS worldwide has increased to 2.8 million in 2020.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Learning Disabilities affect the ability to comprehend, or use spoken or written language, perform
mathematical computations, coordinate motions, or focus attention. Even though they can affect
very young children, learning problems are typically not identified until the kid is of school age.
The estimate for current learning disabilities among children of ages 3–17 years is 7.8 %, with 3.7 %
rated as mild and 4.0 % rated as moderate or severe. Approximately 1,7 % of adults experience
learning disabilities.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Irritable bowel syndrome (IBS) is a common disorder that affects the stomach and intestines, also
called the gastrointestinal tract. Symptoms include cramping, abdominal pain, bloating, gas, and
diarrhea or constipation, or both. IBS is a chronic condition that you'll need to manage long term.
Irritable bowel syndrome affects approximately 10-15% of the European population.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Mild cognitive impairment (MCI) is the stage between the expected decline in memory and thinking
that happens with age and the more serious decline of dementia. MCI may include problems with
memory, language or judgment.
The overall prevalence of MCI is 15.56% worldwide in adults aged 50 years and older. Prevalence
rates of amnestic MCI and non-amnestic MCI is 10.03% and 8.72%.
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Addiction is a compulsive, ongoing, physiological or psychological urge for a habit-forming
substance, action, or activity that has negative physical, psychological, or social impacts and usually
results in well-defined withdrawal or abstinence symptoms such as anxiety, irritability, tremors, or
nausea.
Non-invasive neuromodulation using tDCS “Plato science” device.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
DISEASE & DISORDER
Cancer pain can be managed with various technologies which offer relief to patients when combined
with medication.
Non-invasive neuromodulation using tDCS “Plato science” device.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
DISEASE & DISORDER
ADHD include inattention (not being able to keep focus), hyperactivity (excess movement that is not
fitting to the setting) and impulsivity (hasty acts that occur in the moment without thought)..
ADHD include inattention (not being able to keep focus), hyperactivity (excess movement that is not
fitting to the setting) and impulsivity (hasty acts that occur in the moment without thought).
Non-invasive neuromodulation using tDCS “Plato science” device.
DISEASE & DISORDER
Dementia is a generic term for conditions affecting the memory, thinking skills, and the ability to perform daily activities. With 60-70% of cases, Alzheimer’s disease is the most common form of dementia. While consciousness is not affected, impairment of cognitive function is often accompanied by changes in mood, emotional control, behaviour or motivation.
Worldwide 55 million people have dementia with nearly 10 million new cases every year.
Non-invasive neuromodulation using tDCS "Plato Science" device.
DISEASE & DISORDER
Amyotrophic lateral sclerosis (ALS) is an incurable, severe disease of the central and peripheral nervous system. Motor neurons, that are responsible for controlling and directing muscles and movements are particularly damaged. When the voluntary muscle action is progressively affected, people may lose the ability to speak, eat, move and breathe. Patients suffering from ALS have an average survival time of three years.
ALS has a prevalence of 3.01-7.96 (per 100’000) mainly diagnosed between the age of 40 and 70.
Non-invasive brain stimulation using tDCS. Still under investigation.
DISEASE & DISORDER
Tinnitus is a sensation of sound in the ear or head without an external sound source or electrical stimulus in the environment. Comorbidities include psychological reactions such as insomnia, anxiety, depression, and the lack of concentration.
More than 740 million adults are affected by tinnitus globally.
Non-invasive neuromodulation using tDCS "Plato Science" device.
Transauricular vagus nerve stimulation (taVNS) using Nurosym™ device.
DISEASE & DISORDER
As research in this area progresses, there is evidence that neurostimulation has the potential to improve athletic performance due to its acute effects on motor and cognitive skills as well as its longer-term effects on skill acquisition. According to the World Anti-Doping Authority (WADA), neurostimulation techniques used to improve athletes' performance ability are not considered doping.
Non-invasive neuromodulation using tDCS "Plato Science" device.
NEUROMODULATION
Are you a doctor? SOZΩ Brain Center provides doctors worldwide with the chance to explore our neuromodulation technologies, examine the clinical research, assess our patient outcomes, engage with our diverse scientific team, participate in training seminars regarding our treatment methods and evaluation procedures. Furthermore, we extend an opportunity for doctors to enhance the quality of care in their own practices through our distinctive Partnership Program. Learn more about these opportunities.